complement

Use of Highly Individualized Complement Blockade Has Revolutionized Clinical Outcomes after Kidney Transplantation and Renal Epidemiology of Atypical Hemolytic Uremic Syndrome

Visual Abstracttextlessimg class="highwire-fragment fragment-image" alt="Figure1" src="https://jasn.asnjournals.org/content/jnephrol/30/12/2449/F1.medium.gif" width="440" height="318"/textgreaterDownload figureOpen in new tabDownload …

C5 nephritic factors drive the biological phenotype of C3 glomerulopathies

C3 Glomerulopathies, which include Dense Deposit Disease and C3 Glomerulonephritis, are associated with genetic and acquired dysregulation of the C3 convertase alternative pathway of complement. The potential role of the activation of the C5 …