Irati Garmendia, Aditi Varthaman, Solenne Marmier, Mahmud Angrini, Ingrid Matchoua, Aurélie Darbois-Delahousse, Nathalie Josseaume, Pierre-Emmanuel Foy, Lubka T. Roumenina, Naïra Naouar, Maxime Meylan, Sophie Siberil, Jules Russick, Pierre-Emmanuel Joubert, Karen Leroy, Diane Damotte, Audrey Mansuet-Lupo, Marie Wislez, Marco Alifano, Laurie Menger, Ignacio Garcia-Verdugo, Jean-Michel Sallenave, Olivier Lantz, Florent Petitprez, Isabelle Cremer
(2023).
Acute Influenza Infection Promotes Lung Tumor Growth by Reprogramming the Tumor Microenvironment.
Cancer Immunology Research.
DOI
Yoan Velut, Elise Decroix, Hélène Blons, Marco Alifano, Karen Leroy, Florent Petitprez, Aurélie Boni, Simon Garinet, Jérome Biton, Isabelle Cremer, Marie Wislez, Pascaline Boudou-Rouquette, Jennifer Arrondeau, François Goldwasser, Ludovic Fournel, Diane Damotte, Audrey Mansuet-Lupo
(2022).
SMARCA4-deficient lung carcinoma is an aggressive tumor highly infiltrated by FOXP3+ cells and neutrophils.
Lung Cancer.
DOI
Maxime Meylan, Florent Petitprez, Etienne Becht, Antoine Bougouin, Guilhem Pupier, Anne Calvez, Ilenia Giglioli, Virginie Verkarre, Guillaume Lacroix, Johanna Verneau, Chen-Ming Sun, Pierre Laurent-Puig, Yann-Alexandre Vano, Reza Elaïdi, Arnaud Méjean, Rafaël Sanchez-Salas, Eric Barret, Xavier Cathelineau, Stephane Oudard, Claude-Agnès Reynaud, Aurélien de Reyniès, Catherine Sautès-Fridman, Wolf H. Fridman
(2022).
Tertiary lymphoid structures generate and propagate anti-tumor antibody-producing plasma cells in renal cell cancer.
Immunity.
DOI
Clémentine Decamps, Alexis Arnaud, Florent Petitprez, Mira Ayadi, Aurélia Baurès, Lucile Armenoult, HADACA Consortium, Sergio Escalera, Isabelle Guyon, Rémy Nicolle, Richard Tomasini, Aurélien de Reyniès, Jérome Cros, Yuna Blum, Magali Richard
(2021).
Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression.
BMC Bioinformatics.
PDF
DOI
Jules Russick, Pierre-Emmanuel Joubert, Mélanie Gillard-Bocquet, Carine Torset, Maxime Meylan, Florent Petitprez, Marie Agnes Dragon-Durey, Solenne Marmier, Aditi Varthaman, Nathalie Josseaume, Claire Germain, Gérémy Goc, Marie-Caroline Dieu-Nosjean, Pierre Validire, Ludovic Fournel, Laurence Zitvogel, Gabriela Bindea, Audrey Lupo, Diane Damotte, Marco Alifano, Isabelle Cremer
(2020).
Natural killer cells in the human lung tumor microenvironment display immune inhibitory functions.
Journal for ImmunoTherapy of Cancer.
DOI
Florent Petitprez, Sacha Levy, Cheng-Ming Sun, Maxime Meylan, Christophe Linhard, Etienne Becht, Nabila Elarouci, David Tavel, Lubka T. Roumenina, Mira Ayadi, Catherine Sautès-Fridman, Wolf H. Fridman, Aurélien de Reyniès
(2020).
The murine Microenvironment Cell Population counter method to estimate abundance of tissue-infiltrating immune and stromal cell populations in murine samples using gene expression.
Genome Medicine.
PDF
DOI
Maxime Meylan, Florent Petitprez, Laetitia Lacroix, Luca Di Tommaso, Massimo Roncalli, Antoine Bougoüin, Alexis Laurent, Giuliana Amaddeo, Daniele Sommacale, Hélène Regnault, Jonathan Derman, Cécile Charpy, Fouad Lafdil, Jean-Michel Pawlotsky, Catherine Sautès-Fridman, Wolf H. Fridman, Julien Calderaro
(2020).
Early hepatic lesions display immature tertiary lymphoid structures and show elevated expression of immune inhibitory and immunosuppressive molecules.
Clinical Cancer Research.
DOI
Beth A. Helmink, Sangeetha M. Reddy, Jianjun Gao, Shaojun Zhang, Rafet Basar, Rohit Thakur, Keren Yizhak, Moshe Sade-Feldman, Jorge Blando, Guangchun Han, Vancheswaran Gopalakrishnan, Yuanxin Xi, Hao Zhao, Rodabe N. Amaria, Hussein A. Tawbi, Alex P. Cogdill, Wenbin Liu, Valerie S. LeBleu, Fernanda G. Kugeratski, Sapna Patel, Michael A. Davies, Patrick Hwu, Jeffrey E. Lee, Jeffrey E. Gershenwald, Anthony Lucci, Reetakshi Arora, Scott Woodman, Emily Z. Keung, Pierre-Olivier Gaudreau, Alexandre Reuben, Christine N. Spencer, Elizabeth M. Burton, Lauren E. Haydu, Alexander J. Lazar, Roberta Zapassodi, Courtney W. Hudgens, Deborah A. Ledesma, SuFey Ong, Michael Bailey, Sarah Warren, Disha Rao, Oscar Krijgsman, Elisa A. Rozeman, Daniel Peeper, Christian U. Blank, Ton N. Schumacher, Lisa H. Butterfield, Monika A. Zelazowska, Kevin M. McBride, Raghu Kalluri, James Allison, Florent Petitprez, Wolf Herman Fridman, Catherine Sautès-Fridman, Nir Hacohen, Katayoun Rezvani, Padmanee Sharma, Michael T. Tetzlaff, Linghua Wang, Jennifer A. Wargo
(2020).
B cells and tertiary lymphoid structures promote immunotherapy response.
Nature.
DOI
Florent Petitprez, Aurélien de Reyniès, Emily Z. Keung, Tom Wei-Wu Chen, Cheng-Ming Sun, Julien Calderaro, Yung-Ming Jeng, Li-Ping Hsiao, Laetitia Lacroix, Antoine Bougoüin, Marco Moreira, Guillaume Lacroix, Ivo Natario, Julien Adam, Carlo Lucchesi, Yec′han Laizet, Maud Toulmonde, Melissa A. Burgess, Vanessa Bolejack, Denise Reinke, Khalid M. Wani, Wei-Lien Wang, Alexander J. Lazar, Christina L. Roland, Jennifer A. Wargo, Antoine Italiano, Catherine Sautès-Fridman, Hussein A. Tawbi, Wolf H. Fridman
(2020).
B cells are associated with survival and immunotherapy response in sarcoma.
Nature.
DOI
Julien Zuber, Marie Frimat, Sophie Caillard, Nassim Kamar, Philippe Gatault, Florent Petitprez, Lionel Couzi, Noemie Jourde-Chiche, Valérie Chatelet, Raphael Gaisne, Dominique Bertrand, Jamal Bamoulid, Magali Louis, Rebecca Sberro Soussan, David Navarro, Pierre-Francois Westeel, Luc Frimat, Charlotte Colosio, Antoine Thierry, Joseph Rivalan, Laetitia Albano, Nadia Arzouk, Emilie Cornec-Le Gall, Guillaume Claisse, Michelle Elias, Khalil El Karoui, Sophie Chauvet, Jean-Philippe Coindre, Jean-Philippe Rerolle, Leila Tricot, Johnny Sayegh, Cyril Garrouste, Christophe Charasse, Yahsou Delmas, Ziad Massy, Maryvonne Hourmant, Aude Servais, Chantal Loirat, Fadi Fakhouri, Claire Pouteil-Noble, Marie-Noelle Peraldi, Christophe Legendre, Eric Rondeau, Moglie Le Quintrec, Véronique Frémeaux-Bacchi
(2019).
Use of Highly Individualized Complement Blockade Has Revolutionized Clinical Outcomes after Kidney Transplantation and Renal Epidemiology of Atypical Hemolytic Uremic Syndrome.
Journal of the American Society of Nephrology.
DOI
Khalil El Karoui, Idris Boudhabhay, Florent Petitprez, Paula Vieira-Martins, Fadi Fakhouri, Julien Zuber, Florence Aulagnon, Marie Matignon, Eric Rondeau, Laurent Mesnard, Jean-Michel Halimi, Véronique Frémeaux-Bacchi
(2019).
Impact of hypertensive emergency and rare complement variants on the presentation and outcome of atypical hemolytic uremic syndrome.
Haematologica.
DOI
Anna Maria Di Giacomo, Alessia Covre, Francesca Finotello, Dietmar Rieder, Riccardo Danielli, Luca Sigalotti, Diana Giannarelli, Florent Petitprez, Laetitia Lacroix, Monica Valente, Ornella Cutaia, Carolina Fazio, Giovanni Amato, Andrea Lazzeri, Santa Monterisi, Clelia Miracco, Sandra Coral, Andrea Anichini, Christoph Bock, Amelie Nemc, Aram Oganesian, James Lowder, Mohammad Azab, Wolf H. Fridman, Catherine Sautès-Fridman, Zlatko Trajanoski, Michele Maio
(2019).
Guadecitabine Plus Ipilimumab in Unresectable Melanoma: The NIBIT-M4 Clinical Trial.
Clinical Cancer Research.
DOI
B. Milcent, N. Josseaume, F. Petitprez, Q. Riller, S. Amorim, P. Loiseau, A. Toubert, P. Brice, C. Thieblemont, J.-L. Teillaud, S. Sibéril
(2019).
Recovery of central memory and naive peripheral T cells in Follicular Lymphoma patients receiving rituximab-chemotherapy based regimen.
Scientific Reports.
DOI
Lubka T. Roumenina, Marie V. Daugan, Rémi Noé, Florent Petitprez, Yann A. Vano, Rafaël Sanchez-Salas, Etienne Becht, Julie Meilleroux, Bénédicte Le Clec’h, Nicolas A. Giraldo, Nicolas S. Merle, Cheng-Ming Sun, Virginie Verkarre, Pierre Validire, Janick Selves, Laetitia Lacroix, Olivier Delfour, Isabelle Vandenberghe, Celine Thuilliez, Sonia Keddani, Imene B. Sakhi, Eric Barret, Pierre Ferré, Nathalie Corvaïa, Alexandre Passioukov, Eric Chetaille, Marina Botto, Aurélien de Reynies, Stephane Marie Oudard, Arnaud Mejean, Xavier Cathelineau, Catherine Sautès-Fridman, Wolf H. Fridman
(2019).
Tumor Cells Hijack Macrophage-Produced Complement C1q to Promote Tumor Growth.
Cancer Immunology Research.
DOI
Florent Petitprez, Lea Meunier, Eric Letouze, Yujin Hoshida, Augusto Villanueva, Josep Llovet, Snorri Thorgeirsson, Xin Wei Wang, Wolf H. Fridman, Jessica Zucman-Rossi, Aurelien de Reynies
(2019).
MS.liverK: an R package for transcriptome-based computation of molecular subtypes and functional signatures in liver cancer.
bioRxiv.
PDF
DOI
Marion Dajon, Kristina Iribarren, Florent Petitprez, Solenne Marmier, Audrey Lupo, Mélanie Gillard, Hanane Ouakrim, Navas Victor, Di Bartolo Vincenzo, Pierre Emmanuel Joubert, Oliver Kepp, Guido Kroemer, Marco Alifano, Diane Damotte, Isabelle Cremer
(2019).
Toll like receptor 7 expressed by malignant cells promotes tumor progression and metastasis through the recruitment of myeloid derived suppressor cells.
OncoImmunology.
DOI
Aliyah M. Weinstein, Nicolas A. Giraldo, Florent Petitprez, Catherine Julie, Laetitia Lacroix, Frédérique Peschaud, Jean-François Emile, Laetitia Marisa, Wolf H. Fridman, Walter J. Storkus, Catherine Sautès-Fridman
(2019).
Association of IL-36γ with tertiary lymphoid structures and inflammatory immune infiltrates in human colorectal cancer.
Cancer Immunology, Immunotherapy.
DOI
Nicolas A. Giraldo, Rafael Sanchez-Salas, J. David Peske, Yann Vano, Etienne Becht, Florent Petitprez, Pierre Validire, Alexandre Ingels, Xavier Cathelineau, Wolf Herman Fridman, Catherine Sautès-Fridman
(2018).
The clinical role of the TME in solid cancer.
British Journal of Cancer.
DOI
Julien Calderaro, Florent Petitprez, Etienne Becht, Alexis Laurent, Théo Z. Hirsch, Benoit Rousseau, Alain Luciani, Giuliana Amaddeo, Jonathan Derman, Cécile Charpy, Jessica Zucman-Rossi, Wolf Herman Fridman, Catherine Sautès-Fridman
(2018).
Intra-tumoral tertiary lymphoid structures are associated with a low risk of early recurrence of hepatocellular carcinoma.
Journal of Hepatology.
DOI
Nicolas A. Giraldo, Etienne Becht, Yann Vano, Florent Petitprez, Laetitia Lacroix, Pierre Validire, Rafael Sanchez-Salas, Alexandre Ingels, Stephane Oudard, Audrey Moatti, Benedicte Buttard, Sarah Bourass, Claire Germain, Xavier Cathelineau, Wolf H. Fridman, Catherine Sautès-Fridman
(2017).
Tumor-Infiltrating and Peripheral Blood T-cell Immunophenotypes Predict Early Relapse in Localized Clear Cell Renal Cell Carcinoma.
Clinical Cancer Research.
DOI
Maria-Chiara Marinozzi, Sophie Chauvet, Moglie Le Quintrec, Morgane Mignotet, Florent Petitprez, Christophe Legendre, Mathilde Cailliez, Georges Deschenes, Michel Fischbach, Alexandre Karras, Francois Nobili, Christine Pietrement, Marie-Agnes Dragon-Durey, Fadi Fakhouri, Lubka T. Roumenina, Veronique Fremeaux-Bacchi
(2017).
C5 nephritic factors drive the biological phenotype of C3 glomerulopathies.
Kidney International.
DOI
Florent Petitprez, Nicola Fossati, Yann Vano, Massimo Freschi, Etienne Becht, Roberta Lucianò, Julien Calderaro, Tiffany Guédet, Laetitia Lacroix, Paola M. V. Rancoita, Francesco Montorsi, Wolf Herman Fridman, Catherine Sautès-Fridman, Alberto Briganti, Claudio Doglioni, Matteo Bellone
(2017).
PD-L1 Expression and CD8+ T-cell Infiltrate are Associated with Clinical Progression in Patients with Node-positive Prostate Cancer.
European Urology Focus.
DOI
Sophie Chauvet, Véronique Frémeaux-Bacchi, Florent Petitprez, Alexandre Karras, Laurent Daniel, Stéphane Burtey, Gabriel Choukroun, Yahsou Delmas, Dominique Guerrot, Arnaud François, Moglie Le Quintrec, Vincent Javaugue, David Ribes, Laurence Vrigneaud, Bertrand Arnulf, Jean Michel Goujon, Pierre Ronco, Guy Touchard, Frank Bridoux
(2017).
Treatment of B-cell disorder improves renal outcome of patients with monoclonal gammopathy–associated C3 glomerulopathy.
Blood.
DOI
Sophie Chauvet, Jill Hauer, Florent Petitprez, Marion Rabant, Paula Vieira Martins, VéroniqueBaudouin, Yahsou Delmas, Noémie Jourde-Chiche, Alexandre Cez, David Ribes, Sylvie Cloarec, Aude Servais, Mohamad Zaidan, Eric Daugas, Michel Delahousse, Alain Wynckel, Amélie Ryckewaert, Anne Laure Sellier-Leclerc, Olivia Boyer, Eric Thervet, Alexandre Karras, Richard J.H. Smith, VéroniqueFrémeaux-Bacchi
(2017).
Results from a national-wide retrospective cohort measure the impact of C3 and soluble C5b-9 levels on kidney outcomes in C3 glomerulopathy.
Kidney International.
DOI
Etienne Becht, Nicolas A. Giraldo, Laetitia Lacroix, Bénédicte Buttard, Nabila Elarouci, Florent Petitprez, Janick Selves, Pierre Laurent-Puig, Catherine Sautès-Fridman, Wolf H. Fridman, Aurélien de Reyniès
(2016).
Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression.
Genome Biology.
PDF
DOI